Graduation Year

2018

Date of Submission

12-2017

Document Type

Campus Only Senior Thesis

Degree Name

Bachelor of Arts

Department

Chemistry

Reader 1

Babak Sanii

Reader 2

Joel Mackey

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Terms of Use for work posted in Scholarship@Claremont.

Rights Information

© 2017 Kailee A. Severt

Abstract

Nanomedicine is the fusion between drug therapy and nanotechnology. It is an expanding industry which provides a more efficient and effective way to deliver drugs throughout the body. For individuals suffering from a neurodegenerative disorder, like Huntington’s Disease (HD), current treatments cause major side effects in addition to the disease’s detrimental motor, behavioral and psychiatric symptoms. The goal of the experiment is to encapsulate tetrabenazine, the only FDA approved drug for HD, in a nanoparticle called a micelle. If successful, the new drug nanoparticle can undergo animal testing then clinical trials in hopes of improving patients’ lives.

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