We have developed a high-bandwidth frequency-domain photon migration (FDPM) instrument which is capable of noninvasively determining the optical properties of biological tissues in near-real-time. This portable, inexpensive, diode-based instrument is unique in the sense that we employ direct diode laser modulation and avalanche photodiode detection. Diffusion models were used to extract the optical properties (absorption and transport scattering coefficients)of tissue-simulating solutions.from the 300 kHz to I GHz photon density wave data.
© 1995 International Society of Optical Engineering (SPIE)
Madsen, Steen J., Eric R. Anderson, Richard C. Haskell, and Bruce J. Tromberg. "A high-bandwidth frequency-domain photon migration instrument for clinical use." Proceedings of SPIE: Optical tomography, photon migration, and spectroscopy of tissue and model media: theory, human studies, and instrumentation. Vol. 2389, (1995): 257-263. DOI: 10.1117/12.209976