Title

Two-step, Stereoselective Synthesis of Linalyl Oxides by Asymmetric Allylic O-alkylation

Student Co-author

HMC Undergraduate

Document Type

Article

Department

Chemistry (HMC)

Publication Date

2010

Abstract

Each of the four tetrahydrofuran linalyl oxides was prepared by a Sharpless asymmetric dihydroxylation of geranyl acetate with AD-mix-α or AD-mix-β, followed by a stereoselective palladium-mediated cyclization using the chiral ligand C3-TunePhos.

Rights Information

© 2010 Elsevier Ltd.