Researcher ORCID Identifier
0000-0002-6816-1113
Document Type
Article
Department
Chemistry (Pomona)
Publication Date
5-27-2020
Keywords
SuFEx, calcium bistriflimide, sulfamates, sulfamides, sulfonamides, S(VI) fluorides
Abstract
A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium triflimide and DABCO for SuFEx with amines is described. The reaction was applied to a diverse set of sulfamides, sulfamates, and sulfonamides at room temperature under mild conditions. Additionally, we highlight this transformation to parallel medicinal chemistry to generate a broad array of nitrogen-based S(VI) compounds.
Terms of Use & License Information
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License
DOI
doi.org/10.1021/acs.orglett.0c01397
Recommended Citation
Ball, Nicholas; Mahapatra, Subham; Woroch, Cristian P.; Butler, Todd W.; Carneiro, Sabrina N.; Kwan, Sabrina C.; Khasnavis, Samuel R.; Gu, Junha; Dutra, Jason K.; Vetelino, Beth C.; Bellenger, Justin; and Am Ende, Christopher W., "SuFEx Activation with Ca(NTf2)2: A Unified Strategy to Access Sulfamides, Sulfamates, and Sulfonamides from S(VI) Fluorides" (2020). Pomona Faculty Publications and Research. 494.
https://scholarship.claremont.edu/pomona_fac_pub/494
