Statistical Analysis

Document Type

Book Chapter


Mathematics (Pomona)

Publication Date



Data Analysis, Hypothesis Testing, Confidence Intervals


In this Appendix, we provide an outline of methods used in analyzing molecular biology data. We give a summary of types of data encountered and the appropriate methods to apply for the questions of interest. Statistical techniques described include the t test, the Wilcoxon rank sum test, the Mann-Whitney-Wilcoxon test, ANOVA, regression, and the chi-square test. For each method, we give the appropriate assumptions, the details of the test, and a complete concrete example to follow. We also discuss related ideas such as multiple comparisons and why correlation does not imply causation.

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© 2008 by John Wiley and Sons, Inc.

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