Title

Sulfonamide synthesis via calcium triflimide activation of sulfonyl fluorides

Researcher ORCID Identifier

0000-0002-6816-1113

Document Type

Article

Department

Chemistry (Pomona)

Publication Date

6-11-2018

Keywords

calcium, calcium bistriflimide, SuFEx, sulfonyl fluorides, sulfonamides

Abstract

A method using calcium triflimide [Ca(NTf2)2] as a Lewis acid to activate sulfonyl fluorides toward nucleophilic addition with amines is described. The reaction converts a wide array of sterically and electronically diverse sulfonyl fluorides and amines into the corresponding sulfonamides in good yield.

Comments

0000-0002-6816-1113

Terms of Use & License Information

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

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