Title

Sulfondiimidamides unlocked as new S(VI) hubs for synthesis and drug discovery

Researcher ORCID Identifier

0000-0002-6816-1113

Document Type

Review

Department

Chemistry (Pomona)

Publication Date

3-30-2022

Keywords

perspective, sulfur(VI) fluorides, sulfondiimidamides, chiral, SuFEx

Abstract

Despite their promise as drug targets, access to nitrogen-rich S(VI) compounds has been a significant synthetic challenge. In this issue of Chem, Zhang and Willis explore a new class of S(VI) compounds-sulfondiimidamides-providing robust strategies toward their synthesis, derivation, and promise as new sulfonamide bioisosteres.

Terms of Use & License Information

Terms of Use for work posted in Scholarship@Claremont.

Share

COinS