Date of Award

2026

Degree Type

Open Access Dissertation

Degree Name

Information Systems and Technology, PhD

Program

Center for Information Systems and Technology

Advisor/Supervisor/Committee Chair

Itamar Shabtai

Dissertation or Thesis Committee Member

Warren Roberts

Dissertation or Thesis Committee Member

Zachary Dodds

Dissertation or Thesis Committee Member

Julie Medero & Conrad Shayo

Terms of Use & License Information

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Rights Information

© 2026 Maria Assumpta Komugabe

Keywords

Geographically Weighted Regression, GIS, Machine learning/GEOAI, Malaria Monitoring, Random Forest machine learning, Spatial Autoregressive Models

Subject Categories

Geographic Information Sciences | Public Health

Abstract

Malaria remains a critical public health challenge in Uganda—responsible for an estimated 13.2 million cases annually yet control efforts are continually undermined by climate variability and systemic supply chain failures. This study investigated the relationship between climatic variables (rainfall, temperature, humidity) and malaria incidence, evaluated the efficacy of the current supply management system, and assessed how AI-predictive models and GIS tools can optimize resource distribution. Employing a multi-scalar mixed-methods approach, the research utilized Spatial Autoregressive Models (SAR), Geographically Weighted Regression (GWR), and Random Forest machine learning (R2 = .86) to analyze transmission dynamics. Key findings reveal that minimum temperature is the strongest predictor of transmission (p < .001), while rainfall acts as a reliable 30-day (Lag-1) lead indicator. Emerging Hot Spot Analysis (EHSA) isolated 11 "Intensifying" districts requiring immediate saturation and 32 "Sporadic" zones driven by seasonal volatility. Furthermore, the evaluation of the current supply system exposed a "phantom mortality reduction," where rising stockouts (averaging 53 consecutive days in the Central Region) artificially lowered reported deaths. Significantly, a spatial spillover effect (rho = 0.27) confirmed that uncoordinated interventions fail as high-burden districts export risk to neighboring areas. This research provides three major advancements: methodologically, it combines spatial econometrics with machine learning for high-precision risk forecasting; practically, it introduces an AI-GIS dashboard and Early Warning System to enable a "Self-Healing Supply Chain" and theoretically, the research extends the Health System Resilience Theory established by Kruk et al. (2015) and Blanchet et al. (2017) by introducing the Adaptive Digital Resilience Model (ADRM). Despite these technical gains, the study notes that successful "last mile" delivery depends on closing the digital divide among Village Health Teams (VHTs) to protect the most vulnerable populations.

ISBN

9798244861044

Available for download on Wednesday, November 18, 2026

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