Graduation Year
2018
Date of Submission
12-2017
Document Type
Campus Only Senior Thesis
Degree Name
Bachelor of Arts
Department
Chemistry
Reader 1
Babak Sanii
Reader 2
Joel Mackey
Terms of Use & License Information
Rights Information
© 2017 Kailee A. Severt
Abstract
Nanomedicine is the fusion between drug therapy and nanotechnology. It is an expanding industry which provides a more efficient and effective way to deliver drugs throughout the body. For individuals suffering from a neurodegenerative disorder, like Huntington’s Disease (HD), current treatments cause major side effects in addition to the disease’s detrimental motor, behavioral and psychiatric symptoms. The goal of the experiment is to encapsulate tetrabenazine, the only FDA approved drug for HD, in a nanoparticle called a micelle. If successful, the new drug nanoparticle can undergo animal testing then clinical trials in hopes of improving patients’ lives.
Recommended Citation
Severt, Kailee, "The Micellization of Tetrabenazine as a Nanomedicine for Huntington's Disease" (2018). CMC Senior Theses. 1821.
https://scholarship.claremont.edu/cmc_theses/1821
This thesis is restricted to the Claremont Colleges current faculty, students, and staff.