Graduation Year

2018

Date of Submission

11-2018

Document Type

Open Access Senior Thesis

Degree Name

Bachelor of Arts

Department

Neuroscience

Second Department

W.M. Keck Science Department

Reader 1

John Milton

Reader 2

Dorsa Kay

Terms of Use & License Information

Terms of Use for work posted in Scholarship@Claremont.

Rights Information

© 2018 Austin P Huang

Abstract

Tinnitus is the perception of sound in the absence of an actual sound stimulus. Recent developments have shifted the focus to the central nervous system and the neural correlate of tinnitus. Broadly, tinnitus involves cortical map rearrangement, pathological neural synchrony, and increased spontaneous firing rates. Various cortical regions, such as Heschl’s gyrus in the auditory cortex, have been found to be associated with different aspects of tinnitus, such as perception and loudness. I propose a cortical stimulation mapping study of Heschl’s gyrus using a depth and subdural electrode montage to conduct electrocorticography. This study would provide high-resolution data on abnormal frequency band oscillations characteristic of tinnitus and pinpoint regions where they occur. The validity of the neural synchrony model would also be tested in this study.

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