Portable, High-Bandwidth Frequency-Domain Photon Migration Instrument for Tissue Spectroscopy

Authors

Steen J. Madsen, University of Nevada, Las VegasFollow
Eric R. Anderson, University of California - Irvine
Richard C. Haskell, Harvey Mudd CollegeFollow
Bruce J. Tromberg, University of California - Irvine

Document Type

Article

Department

Physics (HMC)

Publication Date

12-1-1994

Abstract

We describe a novel frequency-domain photon migration instrument employing direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical properties of biological tissues in near real time. An infinite medium diffusion model was used to extract absorption and transport scattering coefficients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed to within 10% of those expected.

Comments

First published in Optics Letters, vol. 19, no. 23 (December 1994), by the Optical Society of America.

Rights Information

©1994 Optical Society of America

Terms of Use & License Information

Terms of Use for work posted in Scholarship@Claremont.

Recommended Citation

Madsen, SJ, Anderson, ER, Haskell, RC, Tromberg, BJ. Portable, high-bandwidth frequency-domain photon migration instrument for tissue spectroscopy. Opt Lett. 1994;19(23): 1934-1936.