Document Type
Article
Department
Physics (HMC)
Publication Date
2-1993
Abstract
The optical properties of brain tissues have been evaluated by measuring the phase velocity and attenuation of harmonically modulated light. The phase velocity for photon density waves at 650-nm wavelength has been found to be in the range of 5 to 12% of the corresponding velocity in a nonscattering medium, and the optical penetration depth was in the range 2.9 to 5.2 mm. These results are used to predict the resolution of optical imaging of deep tissue structures by diffusely propagating incoherent photons. The results indicate that structures of a few millimeters in linear dimension can be identified at 10 mm depth provided that proper wavelength and time resolution are selected. This depth can possibly be enlarged to 30 mm in the case of tissues with very low scattering such as in the case of the neonatal human brain.
Rights Information
© 1993 International Society of Optical Engineering (SPIE)
Terms of Use & License Information
DOI
10.1117/12.60749
Recommended Citation
Svaasand, L.O., B.J. Tromberg, R.C. Haskell, Tsay, T. and M.W. Berns. "Tissue characterization and imaging using photon density waves." Optical Engineering 32.2 (February 1993): 258-266. DOI: 10.1117/12.60749
Comments
Previously linked to as: http://ccdl.libraries.claremont.edu/u?/irw,363.
Pdf acquired through Interlibrary Loan.