Researcher ORCID Identifier

0000-0002-4230-5393

Document Type

Article

Program

Psychology (Pitzer)

Publication Date

2023

Keywords

Polygenic scores, GWAS, Epigenetics, Behavioral genetics

Abstract

Polygenic scores cannot elucidate the mechanisms that produce behavioral phenotypes (including “intelligence”). Therefore, they are unlikely to yield helpful interventions. Moreover, they are poor predictors of individuals’ developmental outcomes. Burt’s critique is well-supported by the details of molecular biology. Specifically, experiences affect epigenetic factors that influence phenotypes via how the genome functions, a fact that lends support to Burt’s conclusions.

Comments

This paper is not the copy of record and may not exactly replicate the authoritative document published by Cambridge University Press at: http://cambridge.org/core/journals/behavioral-and-brain-sciences/article/abs/polygenic-scores-ignore-development-and-epigenetics-dramatically-reducing-their-value/6D7C8EE4A6AF9EEC0FA0FAABFFE9CF98.

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© 2023 The Author

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