Do Longer Delays Matter? The Effect of Prolonging Delay in CTL Activation

Authors

Angela Gallegos, Loyola Marymount University
Ami E. Radunskaya, Pomona CollegeFollow

Document Type

Conference Proceeding

Department

Mathematics (Pomona)

Publication Date

2011

Keywords

dynamical systems, cell behavior, cytotoxic T cell, killer T cell

Abstract

The activation of a specific immune response takes place in the lymphoid organs such as the spleen. We present here a simplified model of the proliferation of specific immune cells in the form of a single delay equation. We show that the system can undergo switches in stability as the delay is increased, and we interpret these results in the context of sustaining an effective immune response to a dendritic cell vaccine.

Rights Information

© 2011 Angela Gallegos and Ami Radunskaya

Terms of Use & License Information

Terms of Use for work posted in Scholarship@Claremont.

Recommended Citation

Gallegos, A. Radunskaya, “Do Longer Delays Matter? The Effect of Prolonging Delay inCTL Activation”. Proceedings of the 8th AIMS International Conference, 2011. http://arxiv.org/abs/1007.0225